Hepatitis A - Medtick

Hepatitis A

What is it?

Viral infection causing swelling of liver and it can become more serious as older one gets.

  • The time taken to develop symptoms can vary from fifteen days to fifty days (normally twenty eight days) after exposure.

  • Most Children aged under six years show no symptoms if illness does occur, it is not usually accompanied by jaundice.
  • Children aged six years and older and adults are more likely to present with signs and symptoms, and have a greater risk of developing fulminant liver failure.

American Medical Association; American Nurses Association-American Nurses Foundation; Centers for Disease Control and Prevention; Center for Food Safety and Applied Nutrition, Food and Drug Administration; Food Safety and Inspection Service, US Department of Agriculture. Diagnosis and management of foodborne illnesses: a primer for physicians and other health care professionals. MMWR Recomm Rep 2004;53(RR-4):1–33. PMID: 15123984


Diagnosis Tests

  • A definitive diagnosis of HAV infection is usually based on the detection of specific immunoglobulin M (IgM) antibodies to the virus (IgM anti-HAV) in the patient’s blood, hence one should have a blood test if one believes they have this condition.

Countries affected are:

Caribbean

  • Anguilla
  • Antigua and Barbuda
  • Aruba
  • Bahamas
  • Barbados
  • Bonaire
  • British Virgin Islands
  • Cayman Islands
  • Cuba
  • Curaçao
  • Dominica
  • Dominican Republic
  • Grenada
  • Guadeloupe
  • Haiti
  • Jamaica
  • Martinique
  • Montserrat
  • Puerto Rico
  • Saba
  • Saint Barthelemy (French Territorial Collectivity)
  • Saint Kitts and Nevis
  • Saint Lucia
  • Saint Martin (French Territorial Collectivity)
  • Sint Eustatius
  • Sint Maarten
  • Trinidad and Tobago
  • Turks and Caicos
  • US Virgin Islands

North America

  • Bermuda
  • Canada
  • Greenland
  • Mexico
  • Saint Pierre and Miquelon
  • United States of America (Alaska, Hawaii, Oahu, Maui)

Central America

  • Belize
  • Costa Rica
  • El Salvador
  • Guatemala
  • Honduras
  • Nicaragua
  • Panama

South America

  • Antarctica (Polar Region)
  • Argentina
  • Bolivia
  • Brazil
  • Chile (Easter Island)
  • Colombia
  • Ecuador (Galapagos Islands)
  • Falkland Islands
  • French Guiana
  • Guyana
  • Paraguay
  • Peru
  • Suriname
  • Uruguay
  • Venezuela (Margarita Island)

Europe & Russia

  • Albania
  • Andorra
  • Armenia
  • Austria
  • Azerbaijan
  • Belarus
  • Belgium
  • Bosnia Herzegovina
  • Bulgaria
  • Croatia
  • Cyprus
  • Czech Republic
  • Denmark
  • Estonia
  • Faroe Islands
  • Finland
  • France (Corsica)
  • Georgia
  • Germany
  • Gibraltar
  • Greece (Corfu, Crete, Rhodes)
  • Hungary
  • Iceland
  • Ireland
  • Italy (Sardinia, Sicily)
  • Kosovo
  • Latvia
  • Liechtenstein
  • Lithuania
  • Luxembourg
  • Malta
  • Monaco
  • Montenegro
  • Netherlands
  • Norway (Svalbard)
  • Poland
  • Portugal (Azores, Madeira)
  • Republic of Moldova
  • Republic of North Macedonia
  • Romania
  • Russian Federation
  • San Marino
  • Serbia
  • Slovakia
  • Slovenia
  • Spain (Spain Majorca, Minorca, Balearic Islands, Ibiza, Formentera, Canary Islands, Gran Canaria, Tenerife, Lanzarote, Fuerteventura)
  • Sweden
  • Switzerland
  • Turkey
  • Ukraine
  • United Kingdom

Africa

  • Algeria
  • Angola
  • Benin
  • Botswana
  • Burkina Faso
  • Burundi
  • Cameroon
  • Cape Verde
  • Central African Republic
  • Chad
  • Comoros
  • Congo
  • Côte d’Ivoire
  • Democratic Republic of Congo
  • Djibouti
  • Egypt
  • Equatorial Guinea
  • Eritrea
  • Eswatini (Swaziland)
  • Ethiopia
  • Gabon
  • Gambia
  • Ghana
  • Guinea
  • Guinea-Bissau
  • Kenya
  • Lesotho
  • Liberia
  • Libya
  • Madagascar
  • Malawi
  • Mali
  • Mauritania
  • Mauritius
  • Mayotte
  • Morocco
  • Mozambique
  • Namibia
  • Niger
  • Nigeria
  • Réunion
  • Rwanda
  • Saint Helena
  • São Tomé and Príncipe
  • Senegal
  • Seychelles
  • Sierra Leone
  • Somalia
  • South Africa
  • South Sudan
  • Sudan
  • Togo
  • United Republic of Tanzania (Zanzibar)
  • Tunisia
  • Uganda
  • Zambia
  • Zimbabwe

Middle East

  • Bahrain
  • Iran
  • Iraq
  • Israel and Occupied Palestinian Territories
  • Jordan
  • Kuwait
  • Lebanon
  • Oman
  • Qatar
  • Saudi Arabia
  • Syria
  • United Arab Emirates (Dubai, Abu Dhabi)
  • Yemen

 

Asia

  • Afghanistan
  • Kazakhstan
  • Kyrgyzstan
  • Pakistan
  • Tajikistan
  • Turkmenistan
  • Uzbekistan
  • Bangladesh
  • Bhutan
  • Brunei Darussalam
  • Cambodia
  • China
  • North Korea
  • Hong Kong
  • Laos
  • Macao
  • Malaysia (Sarawak, Sabah)
  • Maldives
  • Mongolia
  • Myanmar
  • Nepal
  • India
  • Japan
  • Philippines
  • South Korea (Korea, Republic of Korea)
  • Singapore
  • Sri Lanka
  • Taiwan
  • Thailand
  • Timor-Leste
  • Vietnam

Australasia and Pacific

  • American Samoa
  • Australia
  • Christmas Island
  • Cook Islands
  • Federated States Of Micronesia
  • Fiji
  • French Polynesia
  • Guam
  • Kiribati
  • Marshall Islands
  • Nauru
  • New Caledonia
  • New Zealand
  • Niue
  • Northern Mariana Islands
  • Palau
  • Papua New Guinea
  • Pitcairn
  • Samoa
  • Solomon Islands
  • Tokelau
  • Tonga
  • Tuvalu (Ellice Islands)
  • Vanuatu
Ibuprofen and other NSAIDs can be used sparingly under medical supervision, however Ibuprofen and other NSAIDs is not recommended in asthma or asthma type symptoms. Ibuprofen and other NSAIDs should not be used if one has cirrhosis (end-stage liver disease), check with your Medical doctor/Pharmacist when one can have any type of fever reducing medication and the appropriate dose to make sure it suitable for you.

Cause

  • Virus: Hepatovirus (family of Picornaviridae)
  • Poor sanitation and poor sewerage system areas
  • Caught by putting something in the mouth that has been touched by someone who has Hepatitis A by not washing hands properly or poor personal hygiene
  • Drinking infected water or eating salads infected with water (Infection generally occurs following ingestion of food or water that has been contaminated with the faeces of an infected person).
  • Contaminated shellfish and oysters (if not cooked properly)
  • Oral/anal sexual contact (the faecal–oral route, anal to anal)

Treatments

  • Unhygienic injection use (blood transfusions)

Illicit drugs

Symptoms

  • General discomfort (muscle weakness), uneasiness or ill feeling (malaise) and/or fatigue (tiredness)?
  • Aching, painful muscles, muscle cramps/spasms/stiffness?
  • Joint pain and stiffness?
  • High temperature greater than 38°C (100°F) or over and/or chills and sweats longer than 72 hours?
  • Changes in the way things taste or smell (smokers will often develop a sudden distaste for cigarettes)?
  • Pain in the upper right part of the abdomen (generally mild, but constant)?
  • Abdominal pain and/or are constant violently vomiting or vomiting longer than two days?
  • Diarrhoea?
  • Red and/or raised hive rash (especially hepatitis B)?

Then within 2-5 days the infection will trigger the build-up of bilirubin (an orange-yellow pigment produced when the liver breaks down old red blood cells).

Further symptoms include (if these symptoms occurs one needs urgent medical advice):

  • Jaundice (yellowing of skin and whites of the eyes)?
  • Dark coloured urine?
  • Pale or clay-coloured stools?

Complications /Information to beware of/General tips:

Medical Emergency Condition

And/or do not wait, phone for an ambulance if have/develop:


This condition can lead to:

  • Long term tiredness
  • Symptoms can take four to eight weeks to clear
  • The condition can reoccur after several weeks, fully recovery can take up to six months.
  • Cholestatic hepatitis
    • Characterised by a protracted period of jaundice lasting for more than three months with associated pruritus (itchingness), weight loss, diarrhoea and malaise (tiredness).
    • This typically resolves without intervention within 12 weeks with no lasting effects.

Schiff ER. Atypical clinical manifestations of hepatitis A. Vaccine 1992;10(S1):S18–S20. doi: 10.1016/0264-410X(92)90534-Q

  • Aplastic anaemia (i.e. when the body stops producing enough new blood cells)
  • Arthritis
  • Cryoglobulinaemia (i.e. a form of vasculiti- inflammation of the blood vessels)
  • Glomerulonephritis  (i.e. damage to the glomeruli- inflammation of blood vessels in the kidneys);
  • Leukocytoclastic vasculitis (i.e. inflammation of small blood vessels);
  • Myocarditis (i.e. inflammation of the myocardium- heart muscles);
  • Thrombocytopaenia (i.e. abnormally low levels of platelets);
  • Transverse myelitis (i.e. an inflammation of both sides of one section of the spinal cord)

This condition may show similar symptoms to:

Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice

Detailed Information

Please copy and paste any key words from the title: Hepatitis A in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).

  • NHS

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  • Medscape

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  • Pharmaceutical Journal

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  • Healthline

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  • Medical News Today

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  • WebMD

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  • Cleveland Clinic

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  • Mayo Clinic

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  • Drugs.com

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  • National Organisation of Rare Diseases

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  • Verywell Health

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  • Fit for Travel

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  • DR Axe

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