Isaacs’ syndrome is deemed as an autoimmune neuromyotonia disorder which causes persistent muscle fiber contraction characterized by muscle stiffness at rest and impaired muscle relaxation after voluntary contraction.
It affects persons at any age (usually over 40 years old) and symptoms varies significantly in severity.
Cause
Unknown
Autoimmune disease – when the immune system mistakenly attacks certain nerve cells (neurons) that produce glutamic acid decarboxylase (GAD) leading to a deficiency of GABA in the body. GABA helps control muscle movement and prevent hyperexcitability within the brain and spine.
The immune system attacks the protein to amphiphysin, a protein involved in the transmission of signals from one nerve cell to another.
Panic attack or situations that cause a heightened emotional response.
Isaacs syndrome
Our body own immune/defence system attacks our nerves and muscles by producing antibodies that prevent the release of potassium in our nerves endings and this can disrupts the nerve signals between the nerves and muscles.
Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice
Detailed Information
Please copy and paste any key words from the title: Stiff Person Syndrome/Moersch-Woltmann Syndrome/ Isaacs Syndrome in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).
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