Rhinoscleroma | Medtick

Rhinoscleroma

What is it?

A condition which cause lumps in and on the nose, mouth, lips throat and respiratory tract.

  • It occurs normally due to reactivity of capillaries to heat (blood vessels enlarge as react to heat, facial flushing).
  • It is a slow worsening condition bacterial infection and occurs mainly in people of 10-30 years of age and is associated with rosacea.
  • People who have a weak immune system are particularly vulnerable.

It mainly occurs in world regions of:

  • Africa
  • Central and Eastern Europe
  • Central and South America
  • India
  • Middle East
  • The Pacific
  • The Philippines

Diagnosis tests

  • Clinical examination
    • Examine nasal passages for crusting, nodules , narrow nostrils, granuloma masses
    • Anterior rhinoscopy
    • Nasal endoscopy
  • Biopsy
    • Mikulicz cells (large foamy macrophages containing bacteria) to check for formation of granulomatous masses
    • Russell bodies (plasma cells with immunoglobulin inclusions) to check for formation of granulomatous masses
    • Chronic granulomatous inflammation
  • Bacterial culture
  • Histopathological staining
    • Special stains such as PAS or Warthin–Starry may help demonstrate the organisms.
  • CT scan
  • MRI scan
  • PCR test assay

Cause

  • Bacteria: Klebsiella rhinoscerlomatis
    • Spread mainly by respiratory droplets and prolonged close person-to-person contact.
  • It is not highly contagious and usually requires prolonged exposure (Long contact with infected patients).

Higher risk of having condition:

  • Malnutrition
  • Overcrowding (those who have condition can spread to others)
  • Poor hygiene
  • Poor socioeconomic conditions
  • Prolonged close contact with infected individuals
  • Weakened immune system

Symptoms

  • Runny nose, congestion, cold not cleared by over the counter medication or greater than three weeks?
  • Smelly, pussy, runny or blocked nose and dry crusting in the nose up to weeks to months?
  • Lumps form in nose causing nasal blockage and change shape of nose?
  • Nose bleeds?
  • Dry cough longer than three weeks and/or breathing difficulties?
  • Changes in taste, smell and hoarse voice?

Complications /Information to beware of/General tips:

It can lead to eye infections such as:

This condition may show similar symptoms to:

Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice

Detailed Information

Please copy and paste any key words from the title: Rhinoscleroma in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).

  • Medical News Today

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  • Medscape (Professional level)

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  • EveryDay Health

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  • Pharmaceutical Journal (Professional level)

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  • NHS

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  • WebMD

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  • Cleveland Clinic

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  • Mayo Clinic

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  • Drugs.com

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  • National Organisation of Rare Diseases

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  • Verywell Health

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  • Nathnac

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  • DR Axe

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  • Better health - NHS

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