Pagets Disease (Osteitis Deformans) | Medtick
Medtick

Pagets Disease (Osteitis Deformans)

What is it?

Paget’s disease is a bone disorder.

Bones in your body continuously break down and form again in a natural and tightly balanced process called bone re-modelling.

  • This bone re-modelling also occurs in response to stress or injury placed on the bone. For example, weight-bearing exercise leads to increased bone formation.
  • In Paget’s disease, more bone breaks down than usual and more new bone forms than usual.
  • These changes in the bone can lead to bone enlargement and deformity.
  • The new bone growth tends to be softer and more fragile than normal bone, and can develop in a haphazard pattern.
  • Because of this, the bone can fracture.
  • The long bones, especially the legs, tend to bow, and the skull may enlarge, particularly over the forehead.

Harvard health publications 

  • Hence Pagets disease is a long term bone disorder causing the bone not to develop properly resulting in large misshapen abnormal, less dense, brittle, prone to breakage, fractured bone.
  • The method the way the bone grows is affected and causing an increase in calcium levels in the blood that can lead to osteoporosis.
  • It can occur anywhere in the body and symptoms depend on where affected.
    Common areas include spine, thigh bone, pelvis, collarbone, upper arm bone and skull.
  • Symptoms do not always appear until an x-ray and/or blood test  is done
  • Mainly older people get the condition though a rare child condition called Juvenile Paget’s Diseasecan also occur
Paget disease can also affect the nipple and is associated with breast cancer.

Cause

  • Unknown, maybe:
    • Viral condition

Symptoms

  • Bone pain (especially in the back, hips and knees)?
  • Bone deformity [bowing of the thighs (femurs) and lower legs (tibias)]?
  • Big bones (including head) and/or bone growth (spur) causing tingling and numbness locally?
  • Joint stiffness and pain?
  • Osteoporosis?

Paget’s disease of the skull (one has the above symptoms)

  • Headache which is on and off or a constant headache longer than 24 hours?
  • Sensitivity to every day noise and/or ringing noise within and/or difficulty hearing?

Complications /Information to beware of/General tips:

Medical Emergency Condition

And/or do not wait, phone for an ambulance if have or develop:

  • Numbness in joints
  • Blurred vision
  • Bleeding of the nipple

This condition can lead to:

This condition may show similar symptoms to:

Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice

Detailed Information

Please copy and paste any key words from the title: Pagets Disease (Osteitis Deformans) in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).

  • Medical News Today

    Medical news and health news headlines posted throughout the day, every day.

  • Medscape (Professional level)

    Latest medical news and expert commentary in your specialty as well as disease information.

  • Healthline

    Medical Information and health advice you can trust

  • EveryDay Health

    Wellness inspired. Wellness enabled.

  • Pharmaceutical Journal (Professional level)

    The Pharmaceutical Journal covers analysis, features, opinion, learning and careers articles, providing insight and knowledge about drugs, pharmacy practice, medicines use and healthcare policy in the context of the pharmacy profession and pharmaceutical science.

  • NHS

    Find information and advice on health conditions, symptoms, healthy living, medicines and how to get help (British National Health Service).

  • WebMD

    Better Information. Better Health.

  • Cleveland Clinic

    Pushing the Standards of care.

  • Mayo Clinic

    No.1 Hospital in the Nation (America)

  • Drugs.com

    Know more. Be sure.

  • National Organisation of Rare Diseases

    NORD is dedicated to supporting education, elevating care, advancing research, and driving policy for rare diseases.

  • Verywell Health

    Know more. Fell better.

  • Nathnac

    Travel health guidance for health professionals advising travellers and for travellers going overseas from the UK.

  • DR Axe

    Health and fitness news. Recipes, Natural Remedies

  • Better health - NHS

    Healthy changes start with little changes. Whether you want to lose weight, drink less alcohol, get active or quit smoking, you have access to lots of free tools and support through Better Health. You can also find simple ways to lift your mood with Every Mind Matters.

    There has never been a better time to kickstart your health. Let’s do this!

Medtick

© Medtick - 2026. All Rights Reserved.