Sheehan Syndrome - Medtick

Sheehan Syndrome

What is it?

This condition occurs after giving birth (straight after to few months to years later) causing heavy bleeding after labour and can cause severe low blood pressure.


Such extensive bleeding may reduce the blood flow to the pituitary gland causing the pituitary cells to be damaged or die (necrosis).

National Organization of Rare Disorders


Also:

  • During pregnancy and giving birth the pituitary gland enlarges and this could damage the gland and/or not enough oxygen is received by the gland to meets it needs.
  • As a result this can cause the pituitary gland (which supply many hormones to preform various functions in our bodies) not to function as it should because it does not receive enough oxygen and therefore not release the hormones one requires.

The pituitary gland is responsible for the following hormones

  • Growth hormone (GH)
    • This hormone controls bone and tissue growth and maintains the right balance of muscle and fat tissue.
  • Thyroid-stimulating hormone (TSH)
    • This hormone stimulates your thyroid gland to produce key hormones that regulate your metabolism. Shortage of TSH results in an underactive thyroid gland (hypothyroidism)
  • Luteinizing hormone (LH)
    • In women, LH regulates oestrogen.
  • Follicle-stimulating hormone (FSH)
    • Working with LH, FSH helps stimulate egg development and ovulation in women.
  • Adrenocorticotropic hormone (ACTH)
    • This hormone stimulates your adrenal glands to produce cortisol and other hormones.
    • Cortisol helps your body deal with stress and influences many body functions, including blood pressure, heart function and your immune system.
    • A low level of adrenal hormones caused by pituitary damage is called secondary adrenal insufficiency.
  • Prolactin
    • This hormone regulates the development of female breasts, as well as the production of breast milk.

Cause

  • Unknown
  • Damage or injury to pituitary gland
  • Disorder of pituitary gland
  • Lack of oxytocin
  • Placenta conditions
  • Multiple pregnancies

Symptoms

(Symptoms can occur straight away to few months to years later after childbirth)

  • Change in size or shape of either or both breasts/Breast shrinkage?
  • Difficulty to breastfeed or can’t breastfeed?
  • Feel cold?
  • General discomfort (muscle weakness), uneasiness or ill feeling (malaise) and/or fatigue (tiredness)?
  • Lack of period or no menstrual bleed?
  • Loss of pubic hair and/or loss of hair at eye brows?
  • Low blood pressure?
  • Balance and dizziness problems?
  • Difficult to concentrate and/or difficulty in concentrating and/or memory problems and/or slow mental function?
  • Weight gain?
  • Low blood sugar (hypoglycaemia)?
  • Irregular heartbeat?

Complications /Information to beware of/General tips:

Do not wait, phone for an ambulance if have or develop:

  • Patients may present with:
  •  Shock:
    • Rapid heart rate (rapid pulse)
    • Rapid breathing
    • Dilated pupils
    • Pale, cool skin
    • Sweating (diaphoresis)
    • Yawning
  • If shock occurs (whilst awaiting for an ambulance):
    • Lay the person down (if their injuries allow it) and raise and support their legs
    • Use a coat or blanket to keep them warm, but do not cover their face or the burnt area
    • Do not give them anything to eat or drink

This condition can lead to as well as have similar symptoms to:


This condition may show similar symptoms to:

Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice

Detailed Information

Please copy and paste any key words from the title: Sheehan Syndrome in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).

  • NHS

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  • Medscape

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  • Pharmaceutical Journal

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  • Healthline

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  • Medical News Today

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  • WebMD

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  • Cleveland Clinic

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  • Mayo Clinic

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  • Drugs.com

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  • National Organisation of Rare Diseases

    NORD is dedicated to supporting education, elevating care, advancing research, and driving policy for rare diseases.

  • Verywell Health

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  • Fit for Travel

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  • DR Axe

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