Cowden Syndrome - Medtick
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Cowden Syndrome

What is it?

An inherited condition that is characterized primarily by multiple, noncancerous growths (called hamartomas) on various parts of the body.

Persons with the syndrome usually have:

  • Large head (macrocephaly),
  • Benign tumors of the hair follicle (trichilemmomas)
  • White papules with a smooth surface in the mouth (papillomatous papules), starting by the late 20s.
  • It is considered part of the PTEN Hamartoma Tumor Syndrome spectrum which also includes:
  • Persons who have Cowden syndrome are at an increased risk of developing certain types of cancer, such as breast, thyroid, and endometrial (lining of the uterus) cancer

NORD

Cause

  • Unknown
  • Mutations in the PTEN gene and are inherited in an autosomal dominant manner.
  • Family history

Symptoms

Skin changes mainly on face and around mouth:

  • Six or more facial Papules?
  • Three or more Skin tags?
  • Three or more thickened area of skin that is red, brown and yellow?
  • Three or more mouth ulcers?

Hands and feet:

  • Six or more thickened area of skin that is red, brown and yellow on hands or feet?
  • Wart like growths on hands or feet?

Complications /Information to beware of/General tips:

This condition can lead to:

This condition can show similar symptoms to:

Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice

Detailed Information

Please copy and paste any key words from the title: Cowden Syndrome in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).

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