What is it?
Persons with high phosphate levels in the blood occurs when the kidney cannot remove phosphate fast enough.
- In some persons with long term kidney disease, high phosphate levels cause calcium levels in the blood to drop causing low calcium (hypocalcemia symptoms). since phosphate will bind to calcium in the blood.
Disease or conditions causing toxicity
- Kidney cannot remove phosphate fast enough i.e. Kidney failure
- Disorders of the parathyroid hormone gland and related hormones (hypoparathyroidism – where not enough parathyroid hormone gland is produced or Pseudohypoparathyroidism when there is resistance shown by the end -organs to the parathyroid hormone)
- Diabetic ketoacidosis
- Muscle damage /injury
- Infections that cause widespread body symptoms
Treatments
-
Neck irradiation/radioiodine therapy
-
Postparathyroidectomy in dialysis patients
-
Inadvertent surgical removal (can be transient or permanent)
Sign & Symptom of toxicity
- Aching, painful muscles, muscle cramps/spasms/stiffness
- Numbness and tingling around the mouth
- Numbness and tingling in hands
- Numbness and tingling in feet
- Bone pain
- Joint pain and stiffness
- Low mood and Depression
- Confusion
- Rash
- Itchy skin
- Diarrhoea
Nail changes:
Complications /Information to beware of/General tips:
Do not wait, phone for an ambulance if have/develop:
- Heart attack
- Stroke
- Delirium (Medical Emergency)
- Problem with attention (This could mean the person is inattentive and does not focus or that he or she can focus on tasks but at the expense of all else — failure to shift attention.)
- Disorganised thinking (such as not being able to remember things or being confused)
- Altered level of consciousness (hyper-alertness and on edge, or sluggish, drowsy or withdrawn)
- Change is sudden and/or does it fluctuate over hours or days
- Hallucinations
- Seizures
This condition can lead to:
This condition may show similar symptoms to:
Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice
Detailed Information
Please copy and paste any key words from the title: Phosphate Toxicity in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).
- NHS
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- Medscape
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- Verywell Health
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