What is it?
A cleft is a gap or split in the upper lip.
It is present from birth.
The gap is there because parts of the baby’s face did not join together properly during development in the womb.
A cleft lip may just affect one side of the lip or there may be 2 clefts.
It can range from a small notch to a wide gap that reaches the nose.
www.nhs.uk
Cause
Family history
Acrocallosal syndrome Acrocephalopolysyndactyly disorders (Apert syndrome, Chotzen syndrome, Carpenter syndrome, Jackson-Weiss syndrome, Pfeiffer syndrome)Ankyloblepharon-ectodermal dysplasia-cleft lip/palate (AEC) syndrome Arthrogryposis Bohring-Opitz syndrome Branchio-oculo-facial syndrome Branchiootorenal syndrome (pits or ear tags in front of the outer ear)Campomelic syndrome Catel-Manzke syndrome Caudal regression syndrome Cerebrocostomandibular syndrome CHARGE syndrome Cornelia de Lange syndrome Chromosome 10, distal trisomy 10q and other chromosome deletion disorders Cleidocranial dysplasia Craniofrontonasal dysplasia Cri du chat syndrome (cry that resembles the mewing of a cat)Diastrophic dysplasia (disastrophic dwarfism) DiGeorge syndrome Dubowitz syndrome (narrow or triangle-shaped face with a high or sloping forehead, eczema, vision problems)Ellis-Van Creveld syndrome ESCO2 spectrum disorder (Robert syndrome)Femoral facial syndrome Filippi syndrome Frontofacionasal dysplasia Frontonasal dysplasia Fryns syndrome Goltz syndrome Hanhart syndrome Hereditary neuralgic amyotrophy (recurrent episodes of severe pain in the shoulder and arm)Holoprosencephaly Hypomelanosis of Ito (develop areas that lack skin colour)IRF6 -related disordersJackson-Weiss syndrome Johanson-Blizzard syndrome Joubert syndrome Kabuki syndrome Klippel-Feil syndrome Lenz microphthalmia syndrome Marden-Walker syndrome Meckel-Gruber syndrome MEF2C deficiency Miller syndrome Moebius syndrome (eyes do not move from side-to-side, facial paralysis or weakness affecting at least one but usually both sides of the face)Mosaic trisomy 9 Muenke syndrome Neu-Laxova syndrome Oculo-auriculo-vertebral spectrum [abnormalities tend to involve the cheekbones, jaw, mouth, ears, eyes, and/or bones of the spinal column (vertebrae)] – Goldenhar variantOculo-dento-digital dysplasia Oral-facial-digital syndrome Orocraniodigital syndrome Otopalatodigital syndromes type I and II Pallister W syndrome Penta X syndrome Pentalogy of Cantrell Pterygium syndrome Multiple Recessive multiple epiphyseal dysplasia Ring chromosome 4 Robinow syndrome Rubinstein-Taybi syndrome Russell-Silver syndrome Seckel syndrome Simpson-Golabi-Behmel syndrome Smith Lemli Opitz syndrome Sotos syndrome Spondyloepiphyseal dysplasia congenita Stickler syndrome Thrombocytopenia-absent radius syndrome Treacher Collins syndrome Trisomy 13 Syndrome Wolf-Hirschhorn syndrome WDR26 -related disorder (Skraban-Deardorff syndrome)X-linked Opitz G/BBB syndrome
Source: www.carnegieimaging.com
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Complications /Information to beware of/General tips: This condition can lead to:
Difficulty feeding – a baby with a cleft lip and palate may be unable to breastfeed or feed from a normal bottle because they cannot form a good seal with their mouth
Hearing problems :
Some babies with a cleft palate are more vulnerable to ear infections and a build-up of fluid in their ears (glue ear) , which may affect their hearing
Dental problems – a cleft lip and palate can mean a child’s teeth do not develop correctly and they may be at a higher risk of tooth decay.
Speech problems – if a cleft palate is not repaired, it can lead to speech problems such as unclear or nasal-sounding speech when a child is older
www.nhs.uk
Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice
Detailed Information
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