The healing process and inflammation
There are three overlapping phases in the healing process accompanying an injury:
- The initial inflammatory response promotes the influx of inflammatory mediators/agents produced by our own bodies (e.g. leucocytes and macrophages), which effectively clean the injury site of unwanted debris through phagocytosis (the process of engulfing/capturing and destroying particles such as bacteria, parasites, dead host cells, and cellular and foreign debris by a cell).
- Inflammatory mediators/agents produced by our own bodies also provide some protection against infection and the presence of inflammation is in itself part protective, as it significantly reduces movement.
- The vascular element (blood circulation) of the early inflammatory process includes clot formation, scar tissue and rapid increase in the number or amount of blood vessels. The amount of inflammation is related to the extent of vessel damage.
Early appropriate treatment of an injury can enhance recovery by limiting the inflammatory process at an appropriate phase of recovery, hence its important on when to use what medication, the right medication and other treatments and when.
International Association of Athletics Federations. Medical manual Chapter 9: soft tissue damage and healing. Available at: https://www.iaaf.org/about-iaaf/documents/medical (accessed July 2016)
The Pharmaceutical Journal, PJ, August 2016, Vol 297, No 7892;297(7892):
DOI:10.1211/PJ.2016.20201530