Psoriasis Arthritis - Medtick

Psoriasis Arthritis

What is it?

A type of inflammatory arthritis that affects some people with the skin condition psoriasis.

  • Some have the condition psoriasis first and then can progress to psoriasis arthritis
  • Others can have symptoms of arthritis and then have develop a skin condition.
  • Early diagnosis is required to to preserve patients’ joint function, comfort, and independence.

Distinguish from other types of Arthritis

The patterns of joint involvement and which distinguish from other arthritic diseases are as follows:

Each pattern can be seen by itself or in combination with other patterns:

  • Asymmetrical oligoarticular arthritis (arthritis that affects two or more joints in the first 6 months of disease onset)
  • Symmetric polyarthritis- arthritis on both sides of body parts [may mimic rheumatoid arthritis but should be RF- and anti-CCP negative (these are markers tested for inflammatory conditions)]
  • Distal interphalangeal arthropathy (inflammation, bone erosion, the formation of bony nodules on the joint, and swelling in tendons and ligaments  where they attach to the joint of the small joints in the hand)
  • Arthritis mutilans (severe inflammation of joints that often results in joint deformity occurs rarely in patients with psoriatic arthritis, though classification systems vary
  • Spondylitis with or without sacroiliitis (inflammation of the joints in the back bone with or without lower back/buttock pain)
  • Other features are:
    • Swelling around middle of fingers (‘sausage digit’)
    • Skin changes
    • Nail changes

Medscape


Diagnosis Criteria

  • The Classification Criteria for Psoriatic Arthritis (CASPAR) assist clinicians in diagnosing Psoratic arthritis.
  • The CASPAR consist of established inflammatory articular disease with a total of at least 3 points present from the following features (note that one can only score points for one of the three psoriasis criteria):
  • Current psoriasis (2 points)
  • A history of psoriasis (in the absence of current psoriasis; 1 point)
  • A family history of psoriasis (in the absence of current psoriasis and history of psoriasis, 1 point)
  • Dactylitis (1 point) – (‘ swelling’ in the middle of finger- ‘sausage digits’)
  • Juxta-articular (near a joint) new bone formation (1 point)
  • Rheumatoid factor (RF) (marker in blood testing)- negativity (1 point)
  • Nail dystrophy (1 point)

Cause

  • Unknown
  • An autoimmune disease where immune system attacks it own body (in this case joints and the skin)

Although it is thought that factors such as:

Medication

  • Bipolar disease- Lithium
  • High blood pressure, migraines hyperthyroidism and anxiety – B-blockers
  • High blood pressure: ACE inhibitors
  • Quinidine
  • Antimalarial- Chloroquine and hydroxychloroquine
  • Non-steroidal anti-inflammatory drugs (NSAIDs) – Indomethacin
  • Corticosteroids
  • Imiquimod
  • Interferon
  • Terbinafine

Symptoms

  • Pain is all the time and can be worse by movement?
  • General discomfort (muscle weakness), uneasiness or ill feeling (malaise) and/or fatigue (tiredness)?
  • Pain and swelling at the morning and then eases throughout the day?
  • Joint stiffness and pain?
  • Rash, skin nodules (rheumatoid nodules) over the elbows and forearms?
  • Anaemic (lack of oxygen in blood)?
  • Swollen ankles?
  • High temperature greater than 38°C (100°F) or over and/or chills and sweats longer than 72 hours (rheumatic fever)?
  • Cold hand and feet which can be numb and painful?
  • Hard Painless lump and/or not moving and and/or is becoming larger?
  • Dry, red skin patches (plaques) on white skin (purple colour in black skin) covered in silvery scales?
  • Silvery scales flake off easily when scratched/touched and is hot/red/tender underneath?
  • Inflamed sore hot skin which can be angry and/or burning skin?
  • Red patch(s) has a sharp border/edge with normal skin?
  • Small white pustules that spread and join together to form what is referred to as “lakes of pus,” which eventually peel off in a sheet-like pattern to reveal hot, red and swollen underlying skin (deep red rash and burnt looking skin)?
  • Rash mainly occur on the outer joints (though can occur on any part of body)?
  • Experience skin flare-ups (they could happen regularly or from time to time)?
  • Itchy skin?

Nail changes:

Complications /Information to beware of/General tips:

Do not wait, phone for ambulance if have or develop:


This condition can lead to:


This condition can be associated with:

  • Celiac disease
  • Adult Still’s disease
  • Caplan syndrome
  • Synovotis
    • The knee, ankle, wrist, elbow, hand, foot, and shoulder are synovial hinge joints, and as such the joint is lined with a synovial membrane.
    • If this membrane becomes inflamed it is called synovitis.
    • It is caused by overuse or trauma and results in repeated bleeds into the joint.
    • If not treated early or correctly the synovial membrane becomes thickened with more blood vessels and becomes swollen and painful.
    • It is also associated with:

This condition may show similar symptoms to:

This condition may show similar symptoms to if pain occurring on the back, hip and shoulders:

  • Arthritis
  • Spinal tumour
  • Exostosis (Osteoma)
  • Ankylosing Spondylitis
  • Arthritis related to inflammatory bowel disease
  • SAPHO syndrome (rare inflammatory disorder of bone, joints, and skin):
    • Synovitis- joints become swollen
    • Acne
    • Pustulosis- highly inflammatory skin condition resulting in large fluid-filled blister-like areas – pustules.
      • Pustulosis typically occurs on the palms of the hands and/or the soles of the feet. The skin of these areas peels and flakes (exfoliates).
    • Hyperostosis
    • Osteitis- inflammation, hot, red and swollen bones.
  • Reactive arthritis

Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice

Detailed Information

Please copy and paste any key words from the title: Psoriasis Arthritis in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).

  • NHS

    Find information and advice on health conditions, symptoms, healthy living, medicines and how to get help (British National Health Service).

  • Medscape

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  • Pharmaceutical Journal

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  • Healthline

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  • Medical News Today

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  • WebMD

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  • Cleveland Clinic

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  • Mayo Clinic

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  • Drugs.com

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  • National Organisation of Rare Diseases

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  • Verywell Health

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  • Fit for Travel

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  • DR Axe

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