Newborn Respiratory Distress Syndrome - Medtick

Newborn Respiratory Distress Syndrome

What is it?

New born respiratory distress syndrome (NRDS) happens when a baby’s lungs are not fully developed and cannot provide enough oxygen, causing breathing difficulties.

  • It usually affects premature babies.
  • NRDS usually occurs when the baby’s lungs have not produced enough surfactant.
  • Surfactant is a foamy substance that keeps the lungs fully expanded so that newborns can breathe in air once they are born.
  • This substance, made up of proteins and fats, helps keep the lungs inflated and prevents them collapsing.
  • Without enough surfactant, the lungs collapse and the new born has to work hard to breathe. He or she might not be able to breathe in enough oxygen to support the body’s organs especially the brain.
  • A baby normally begins producing surfactant sometime between weeks 24 and 28 of pregnancy.
  • Most babies produce enough to breathe normally by week 34.
  • If ones baby is born prematurely, they may not have enough surfactant in their lungs.
  • It is also known as:
    • Respiratory distress syndrome
    • Hyaline membrane disease
    • Surfactant deficiency lung disease

Cause

  • Born prematurely
    • Not have enough surfactant in their lungs – The earlier your baby is born, the greater his or her risk .
    • Most cases of RDS occur in babies born before 28 weeks of pregnancy.
  • Stress during your baby’s delivery, especially if mother loses a lot of blood
  • Require an emergency cesarean delivery before your baby is full term
  • Mother has had gestational diabetes and/or diabetes
    • In mothers with diabetes, consistently elevated levels of glucose result in excess insulin production by the fetus (Fetal hyperinsulinemia) can affect lung maturity and alter the synthesis of lung surfactant, increasing the risk for respiratory distress.
    • The risk for respiratory distress is higher in patients with an elective cesarean section, which is common among mothers with diabetes, compared with patients with who have elective labour method.
    • In addition, maternal glucose supply (glucose from the mother)  is abruptly ended at delivery but hyperinsulinemia (insulin produced by the foetus/baby) continues, this may result in hypoglycaemia shortly after birth.
  • Infection
  • Baby is underweight
  • Babies lungs have not develop properly (during screening , steroidal medication is given to the mother during premature labour)
  • Chromosome 5, Trisomy 5p
  • Citrullinemia type I (CTLN1)
  • Generalized arterial calcification (infants)
  • Glutaric aciduria type II

Syndromes

Symptoms

The symptoms of NRDS are often noticeable immediately after birth and get worse over the following 24 hours to the next few days.

NHS


  • Blue-coloured lips, fingers and toes?
  • Rapid and/or shallow breathing?
  • Sharp pulling inward of the muscles between the ribs when breathing?
  • Pauses in breathing that last for a few seconds (apnea)?
  • Flaring nostrils?
  • Grunting sound when breathing?

Complications /Information to beware of/General tips:

Medical Emergency Condition

And/or do not wait, phone for an ambulance

This condition can lead to (all are Medical Emergencies):

  • Cerebral palsy
  • Sepsis
  • Kidney failure
  • Necrotizing enterocolitis (bowel condition): Symptoms include:
    • A swollen, red, or tender belly.
    • Trouble feeding.
    • Food staying in the stomach longer than expected.
    • Constipation.
    • Diarrhoea and/or dark or bloody stools (poop)
    • Being less active or lethargic.
    • a low or unstable body temperature.
    • Green vomit (containing bile)
  • Patent ductus arteriosus, a type of congenital heart defect. The ductus arteriosus connects pulmonary arteries to the aorta. If it remains open, it can strain the heart and increase blood pressure in the lung arteries: Symptoms include:
    • Fast breathing, working hard to breathe, or shortness of breath?
    • Poor feeding and poor weight gain?
    • Tiring easily?
    • Sweating with exertion, such as while feeding?

This condition can lead to:

  • Pneumothorax
    • Air can sometimes leak out of the baby’s lungs and become trapped in their chest cavity. The pocket of air places extra pressure on the lungs, causing them to collapse and leading to additional breathing problems.
    • Air leaks can be treated by inserting a tube into the chest to allow the trapped air to escape.
  • Internal bleeding
    • Babies with NRDS may have bleeding inside their lungs (pulmonary haemorrhage) and brain (cerebral haemorrhage).
    • Bleeding into the lungs is treated with air pressure from a ventilator to stop the bleeding and a blood transfusion.
    • Bleeding into the brain is quite common in premature babies, but most bleeds are mild and do not cause long-term problems.
  • Lung scarring
    • Sometimes ventilation (begun within 24 hours of birth) or the surfactant used to treat NRDS causes scarring to the baby’s lungs, which affects their development.
    • This lung scarring is called:
      Bronchopulmonary dysplasia (BPD)
    • Symptoms of BPD include rapid, shallow breathing and shortness of breath.
    • Babies with severe BPD usually need additional oxygen from tubes into their nose to help with their breathing.
    • This is usually stopped after a few months, when the lungs have healed.
    • But children with BPD may need regular medication, such as bronchodilators, to help widen their airways and make breathing easier.

NHS


  • Some of the life-saving treatments used for NRDS may contribute to BPD. Some newborns who have RDS recover and never get BPD.

National Heart, Lung and Blood Institute


For this condition an oxygen ventilator maybe used to provide more oxygen to ones lungs.

Complications include:

  • Pulmonary embolism– blood clots can form (in the vessels of your  arms and/or legs) especially when on a ventilator and one is doing no form of exercise. The blood clot can break off and travel to the lungs.
  • Collapsed lung (pneumothorax) -A breathing machine called a ventilator is used to increase oxygen in the body and force fluid out of the lungs. however, the pressure and air volume of the ventilator can force gas to go through a small hole in the very outside of a lung and cause that lung to collapse.
  • Infections – Because the ventilator is attached directly to a tube inserted in your windpipe, this makes it much easier for germs to infect and further injure your lungs.

MayoClinic


This condition can lead to (because of bleeding or a lack of oxygen):

  • Learning difficulties
  • Poor memory and thinking clearly- due to low oxygen levels and sedation
  • Neurological conditions (nerve damage)
  • Muscle disorders and/or damage
  • Impaired hearing
  • Impaired vision
  • Scarring (pulmonary fibrosis)- Scarring and thickening of the tissue between the air sacs can occur within a few weeks of the onset of ARDS. This stiffens your lungs, making it even more difficult for oxygen to flow from the air sacs into your bloodstream.
  • Long lasting damage to lungs (while others make a good recovery).

This condition may show similar symptoms to:

Detailed Information

Please copy and paste any key words from the title: Newborn Respiratory Distress Syndrome in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).

  • NHS

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