According to the University of Chicago Medicine, it accounts for about 90 percent of cases. Someone who has a parent with PKD has a 50 percent chance of developing this condition.
Symptoms usually develop later in life, between the ages of 30 and 40. However, some people begin to experience symptoms in childhood.
Autosomal recessive PKD
Autosomal recessive PKD (ARPKD) is much less common than ADPKD.
It’s also inherited, but both parents must carry the gene for the disease.
People who are carriers of ARPKD won’t have symptoms if they have only one gene. If they inherit two genes, one from each parent, they’ll have ARPKD.
There are four types of ARPKD:
Perinatal form is present at birth.
Neonatal form occurs within the first month of life.
Infantile form occurs when the child is 3 to 12 months old.
Juvenile form occurs after the child is 1 year old.
ACKD usually develops in people who already have other kidney problems. It’s more common in people who have kidney failure or are on dialysis.
Healthline.com
Cause
Inherited disease (family history)
Autosomal Dominant PKD (AD-PKD): Mutation of PKD1 , PKD2, or PKD3 genes (depending on the genes mutated and type of mutation can have a huge effect on the expected outcome of PKD.
PKD1 gene mutations (more aggressive) where patients could develop kidney failure in their mid 50s.
PKD2 mutation (less severe in females )cysts develop much later, and renal failure typically does not occur until as late as the mid 70s.
Townes-Brocks syndrome [A closed anal opening (imperforate anus), small ears that usually have a folded rim of skin and cartilage around the outer ear, and differences in the structures of the thumbs]
Please talk to your healthcare professional (i.e. Medical Doctor/Pharmacist) for further advice
Detailed Information
Please copy and paste any key words from the title: Polycystic kidney disease in the following respective 'Medtick References and/or Sources' to find out more about the disease (this also may include diagnosis tests and generic medical treatments).
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